Role of mutator alleles in adaptive evolution
نویسندگان
چکیده
منابع مشابه
Fitness evolution and the rise of mutator alleles in experimental Escherichia coli populations.
We studied the evolution of high mutation rates and the evolution of fitness in three experimental populations of Escherichia coli adapting to a glucose-limited environment. We identified the mutations responsible for the high mutation rates and show that their rate of substitution in all three populations was too rapid to be accounted for simply by genetic drift. In two of the populations, lar...
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ژورنال
عنوان ژورنال: Nature
سال: 1997
ISSN: 0028-0836,1476-4687
DOI: 10.1038/42696